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[Articles] Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1

Gio, 15/07/2021 - 01:01
After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines.

[Articles] Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study

Gio, 15/07/2021 - 01:01
Routine immunisation services faced stark challenges in 2020, with the COVID-19 pandemic causing the most widespread and largest global disruption in recent history. Although the latest coverage trajectories point towards recovery in some regions, a combination of lagging catch-up immunisation services, continued SARS-CoV-2 transmission, and persistent gaps in vaccine coverage before the pandemic still left millions of children under-vaccinated or unvaccinated against preventable diseases at the end of 2020, and these gaps are likely to extend throughout 2021.

[Seminar] Lung cancer

Gio, 15/07/2021 - 00:30
Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related deaths worldwide with an estimated 2 million new cases and 1·76 million deaths per year. Substantial improvements in our understanding of disease biology, application of predictive biomarkers, and refinements in treatment have led to remarkable progress in the past two decades and transformed outcomes for many patients. This seminar provides an overview of advances in the screening, diagnosis, and treatment of non-small-cell lung cancer and small-cell lung cancer, with a particular focus on targeted therapies and immune checkpoint inhibitors.

[Correspondence] Education and mental health: good reasons to vaccinate children

Gio, 15/07/2021 - 00:30
With the elevated transmissibility of circulating SARS-CoV-2 variants, vaccination coverages as high as 90% in adults might be necessary to fully relax control measures towards the end of 2021.1 Such targets might be hard to reach because of vaccine hesitancy. Therefore, there is a risk that COVID-19 might cause substantial stress on health care in the winter months at the end of 2021 and beginning of 2022. Modelling data suggest that vaccination of children and adolescents could help mitigate this risk of SARS-CoV-2 dissemination by ensuring they do not act as a reservoir.

[Correspondence] COVAX: more than a beautiful idea

Gio, 15/07/2021 - 00:30
Ann Usher1 reported that COVAX was a ship that was being built as it set sail, and the challenges described, although inaccurate in many of the details, have indeed led to serious initial setbacks. But Usher wholly misses the point that this is a ship that is still sailing.