Science[Report] Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric GlioblastomaMutations of histones in some cancers result in inhibition of enzymes that lay down epigenetic marks on chromatin. [Also see Perspective by Morgan and Shilatifard]
Authors: Peter W. Lewis, Manuel M. Müller, Matthew S. Koletsky, Francisco Cordero, Shu Lin, Laura A. Banaszynski, Benjamin A. Garcia, Tom W. Muir, Oren J. Becher, C. David Allis Categorie: Riviste scientifiche
[Report] Invasive Harlequin Ladybird Carries Biological Weapons Against Native CompetitorsInvasive ladybugs harbor microsporidia that kill nonresistant beetles contributing to the original residents’ decline. [Also see Perspective by Reynolds]
Authors: Andreas Vilcinskas, Kilian Stoecker, Henrike Schmidtberg, Christian R. Röhrich, Heiko Vogel Categorie: Riviste scientifiche
[Report] Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MALA dynamic polymeric actin structure inside the nucleus is part of the serum response in mammalian tissue culture cells.
Authors: Christian Baarlink, Haicui Wang, Robert Grosse Categorie: Riviste scientifiche
[Report] Wnt Stabilization of β-Catenin Reveals Principles for Morphogen Receptor-Scaffold AssembliesThe scaffold protein Axin has an active role in modulating signaling through the Wnt pathway.
Authors: Sung-Eun Kim, He Huang, Ming Zhao, Xinjun Zhang, Aili Zhang, Mikhail V. Semonov, Bryan T. MacDonald, Xiaowu Zhang, Jose Garcia Abreu, Leilei Peng, Xi He Categorie: Riviste scientifiche
[Report] Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling ComplexesA scaffold protein provides a two-step regulatory mechanism to control the exit from mitosis in yeast.
Authors: Jeremy M. Rock, Daniel Lim, Lasse Stach, Roksana W. Ogrodowicz, Jamie M. Keck, Michele H. Jones, Catherine C. L. Wong, John R. Yates III, Mark Winey, Stephen J. Smerdon, Michael B. Yaffe, Angelika Amon Categorie: Riviste scientifiche
[Report] ATAXIN-2 Activates PERIOD Translation to Sustain Circadian Rhythms in DrosophilaFruit fly circadian clock function requires protein translation regulated by an RNA-binding protein.
Authors: Chunghun Lim, Ravi Allada Categorie: Riviste scientifiche
[Report] A Role for Drosophila ATX2 in Activation of PER Translation and Circadian BehaviorFruit fly circadian clock function requires protein translation regulated by an RNA-binding protein.
Authors: Yong Zhang, Jinli Ling, Chunyan Yuan, Raphaëlle Dubruille, Patrick Emery Categorie: Riviste scientifiche
New ProductsA weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
Categorie: Riviste scientifiche
[Podcast] Science Podcast: 17 May ShowListen to stories on fracking, troubling science software, the science of taste, and more.
Categorie: Riviste scientifiche
[Review] Impact of Shale Gas Development on Regional Water QualityAuthors: R. D. Vidic, S. L. Brantley, J. M. Vandenbossche, D. Yoxtheimer, J. D. Abad Categorie: Riviste scientifiche
This Week in ScienceSimulating Foam Formation | Defense and Counter-Defense | Building Better Vaccines | A Phase for Fano | Making Metamaterials | Dust in the Clouds | Setting the Pace | Identical and Still Different | Infections Against Infection | Of Mice and Markets | Creating Unstable Atomic Orbitals | bZIPping Through Evolution | Keeping in Synch | Getting It Wright? | Dendritic Precision Strikes
Categorie: Riviste scientifiche
Editors' ChoiceBiomedicine: The Benefits of Sequestration | Education: Motivation + Skill = Success | Animal Behavior: A Social Shake-up by Song | Chemistry: Brushing Away Toxicity | Chemistry: Mimicking Rodlike Viruses | Biomedicine: Peptide Prevention | Biochemistry: Attacked by Radicals
Categorie: Riviste scientifiche
FindingsMore Clues to Origins of Frog-Killing Fungus | Slow Malaria: Infect Mosquitoes
Categorie: Riviste scientifiche
[News of the Week] Around the WorldIn science news around the world, the Large Millimeter Telescope will begin its first scientific observation season next week, journals are being asked to help tighten U.S. trade sanctions on Iran, and a new research challenge seeks studies that reveal differences between males and females in the development of Alzheimer's disease.
Categorie: Riviste scientifiche
[News of the Week] NewsmakersScience speaks with microbiologist George F. Gao, who is in the trenches of the H7N9 avian influenza outbreak that has killed 27 people in China since March. And after 26 years, Eugenie Scott, the founding executive director of the National Center for Science Education, has announced her retirement.
Categorie: Riviste scientifiche
[News of the Week] Random SampleWhen settlers in the Jamestown, Virginia, colony ran out of food in the winter of 1609, some contemporary records suggest they resorted to eating each other. Now, scientists have found the first physical evidence that they did. And rumors surrounding a bizarre 6-inch-long skeleton have been put to rest with scientists confirming that the specimen is human.
Categorie: Riviste scientifiche
[News & Analysis] Aids Research: More Woes for Struggling HIV Vaccine FieldDevastating results from two trials have sent researchers scrambling—again.
Author: Jon Cohen Categorie: Riviste scientifiche
[News & Analysis] NASA: Planetary Scientists Casting Doubt on Feasibility of Plan to Corral AsteroidNASA's new plan to capture a tiny asteroid and lodge it in the Earth-moon system is certainly audacious, but many have doubts.
Author: Richard A. Kerr Categorie: Riviste scientifiche
[News & Analysis] U.S. Science Policy: Proposed Change in Awarding Grants at NSF Spurs Partisan SnipingDebate continues over a bill that might allow Congress to intrude on the peer-review process
Author: Jeffrey Mervis Categorie: Riviste scientifiche
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