Science

Condividi contenuti Science
The best in science news, commentary, and research
Aggiornato: 6 ore 54 min fa

[Report] Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

Gio, 16/05/2013 - 23:44
Mutations of histones in some cancers result in inhibition of enzymes that lay down epigenetic marks on chromatin. [Also see Perspective by Morgan and Shilatifard]

Authors: Peter W. Lewis, Manuel M. Müller, Matthew S. Koletsky, Francisco Cordero, Shu Lin, Laura A. Banaszynski, Benjamin A. Garcia, Tom W. Muir, Oren J. Becher, C. David Allis

[Report] Invasive Harlequin Ladybird Carries Biological Weapons Against Native Competitors

Gio, 16/05/2013 - 23:44
Invasive ladybugs harbor microsporidia that kill nonresistant beetles contributing to the original residents’ decline. [Also see Perspective by Reynolds]

Authors: Andreas Vilcinskas, Kilian Stoecker, Henrike Schmidtberg, Christian R. Röhrich, Heiko Vogel

[Report] Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL

Gio, 16/05/2013 - 23:44
A dynamic polymeric actin structure inside the nucleus is part of the serum response in mammalian tissue culture cells.

Authors: Christian Baarlink, Haicui Wang, Robert Grosse

[Report] Wnt Stabilization of β-Catenin Reveals Principles for Morphogen Receptor-Scaffold Assemblies

Gio, 16/05/2013 - 23:44
The scaffold protein Axin has an active role in modulating signaling through the Wnt pathway.

Authors: Sung-Eun Kim, He Huang, Ming Zhao, Xinjun Zhang, Aili Zhang, Mikhail V. Semonov, Bryan T. MacDonald, Xiaowu Zhang, Jose Garcia Abreu, Leilei Peng, Xi He

[Report] Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes

Gio, 16/05/2013 - 23:44
A scaffold protein provides a two-step regulatory mechanism to control the exit from mitosis in yeast.

Authors: Jeremy M. Rock, Daniel Lim, Lasse Stach, Roksana W. Ogrodowicz, Jamie M. Keck, Michele H. Jones, Catherine C. L. Wong, John R. Yates III, Mark Winey, Stephen J. Smerdon, Michael B. Yaffe, Angelika Amon

[Report] ATAXIN-2 Activates PERIOD Translation to Sustain Circadian Rhythms in Drosophila

Gio, 16/05/2013 - 23:44
Fruit fly circadian clock function requires protein translation regulated by an RNA-binding protein.

Authors: Chunghun Lim, Ravi Allada

[Report] A Role for Drosophila ATX2 in Activation of PER Translation and Circadian Behavior

Gio, 16/05/2013 - 23:44
Fruit fly circadian clock function requires protein translation regulated by an RNA-binding protein.

Authors: Yong Zhang, Jinli Ling, Chunyan Yuan, Raphaëlle Dubruille, Patrick Emery

New Products

Gio, 16/05/2013 - 23:44
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

[Podcast] Science Podcast: 17 May Show

Gio, 16/05/2013 - 23:44
Listen to stories on fracking, troubling science software, the science of taste, and more.

[Review] Impact of Shale Gas Development on Regional Water Quality

Gio, 16/05/2013 - 23:44


Authors: R. D. Vidic, S. L. Brantley, J. M. Vandenbossche, D. Yoxtheimer, J. D. Abad

This Week in Science

Gio, 09/05/2013 - 21:33
Simulating Foam Formation | Defense and Counter-Defense | Building Better Vaccines | A Phase for Fano | Making Metamaterials | Dust in the Clouds | Setting the Pace | Identical and Still Different | Infections Against Infection | Of Mice and Markets | Creating Unstable Atomic Orbitals | bZIPping Through Evolution | Keeping in Synch | Getting It Wright? | Dendritic Precision Strikes

Editors' Choice

Gio, 09/05/2013 - 21:33
Biomedicine: The Benefits of Sequestration | Education: Motivation + Skill = Success | Animal Behavior: A Social Shake-up by Song | Chemistry: Brushing Away Toxicity | Chemistry: Mimicking Rodlike Viruses | Biomedicine: Peptide Prevention | Biochemistry: Attacked by Radicals

Findings

Gio, 09/05/2013 - 21:33
More Clues to Origins of Frog-Killing Fungus | Slow Malaria: Infect Mosquitoes

[Editorial] On Effective Leadership

Gio, 09/05/2013 - 21:33
Author: Bruce Alberts

[News of the Week] Around the World

Gio, 09/05/2013 - 21:33
In science news around the world, the Large Millimeter Telescope will begin its first scientific observation season next week, journals are being asked to help tighten U.S. trade sanctions on Iran, and a new research challenge seeks studies that reveal differences between males and females in the development of Alzheimer's disease.

[News of the Week] Newsmakers

Gio, 09/05/2013 - 21:33
Science speaks with microbiologist George F. Gao, who is in the trenches of the H7N9 avian influenza outbreak that has killed 27 people in China since March. And after 26 years, Eugenie Scott, the founding executive director of the National Center for Science Education, has announced her retirement.

[News of the Week] Random Sample

Gio, 09/05/2013 - 21:33
When settlers in the Jamestown, Virginia, colony ran out of food in the winter of 1609, some contemporary records suggest they resorted to eating each other. Now, scientists have found the first physical evidence that they did. And rumors surrounding a bizarre 6-inch-long skeleton have been put to rest with scientists confirming that the specimen is human.

[News & Analysis] Aids Research: More Woes for Struggling HIV Vaccine Field

Gio, 09/05/2013 - 21:33
Devastating results from two trials have sent researchers scrambling—again.

Author: Jon Cohen

[News & Analysis] NASA: Planetary Scientists Casting Doubt on Feasibility of Plan to Corral Asteroid

Gio, 09/05/2013 - 21:33
NASA's new plan to capture a tiny asteroid and lodge it in the Earth-moon system is certainly audacious, but many have doubts.

Author: Richard A. Kerr

[News & Analysis] U.S. Science Policy: Proposed Change in Awarding Grants at NSF Spurs Partisan Sniping

Gio, 09/05/2013 - 21:33
Debate continues over a bill that might allow Congress to intrude on the peer-review process

Author: Jeffrey Mervis